The benefits of using capacitance as a direct measurement of cell density and health in bioprocessing

Dielectric spectroscopy has been successfully used in the bioprocess industry to measure cell density in bioreactors for close to three decades. With FDA’s PAT initiative, capacitance based cell density measurements have become even more relevant and valuable.

The ability to measure viable cells exclusively, in-situ and in real time makes this technology stand apart from others. Over the years, it has been used for a variety of applications that include not only monitoring the cells, but also automatically controlling a critical aspect of the process.

In addition to this, a number of cGMP bioprocessing facilities have advanced to using capacitance as a direct measurement of cell health and as their ‘gold standard’ for process control.

Real-time monitoring
& control
control complex
feed rates
Sensors for
conventional &
single use biorectors

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