Publications

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells

Real‐Time Auto Controlling of Viable Cell Density in Perfusion Cultivation Aided by In‐Line Dielectric Spectroscopy With Segmented Adaptive PLS Model

Impact of fed-batch process intensification on the productivity and product quality of two CHO cell lines expressing unique novel molecular format proteins

A modular and multi-functional purification strategy that enables a common framework for manufacturing scale integrated and continuous biomanufacturing

An automated high inoculation density fed-batch bioreactor, enabled through N-1 perfusion, accommodates clonal diversity and doubles titers

Reduction of medium consumption in perfusion mammalian cell cultures using a perfusion rate equivalent concentrated nutrient feed

How capacitance measurement can improve viral vector and virus-based vaccine production – BPI Special report

Real-time monitoring and control of CHO cell apoptosis by in situ multifrequency scanning dielectric spectroscopy

Case study: The characterization and implementation of dielectric spectroscopy (biocapacitance) for process control in a commercial GMP CHO manufacturing process

Development of Capacitance Tools: At-Line Method for Assessing Biomass of Mammalian Cell Culture and Fixed Cell Calibration Standard

Advanced process monitoring and feedback control to enhance cell culture process production and robustness, Biotechnology and Bioengineering

Immobilised Cells – Microcarriers

3D Cellular Constructs

Biomass Fermentation – Filamentous Fungi

Scale up

Viral Vector Production

Online Cell culture in cGMP

Monitoring CHO Cell Culture Processes

Utilising capacitance measurement to improve vaccine and viral vector production

Microbial

Optimized Perfusion by Capacitance Process Measurement and Control

Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition

Development of a shake tube-based scale-down model for perfusion cultures

The effects of alternating tangential flow (ATF) residence time, hydrodynamic stress, and filtration flux on high-density perfusion cell culture

Isotope labeling to determine the dynamics of metabolic response in CHO cell perfusion bioreactors using MALDI-TOF-MS

On-line Measurements and Control of Viable Cell Density in Cell Culture Manufacturing Processes using Radio-frequency Impedance

Optimization and control of perfusion cultures using a viable cell probe and cell specific perfusion rates